ER 1-D5 expression in normal rat mammary duct.
Detection with Biogenex Super Sensitive HRP
kit. Positive nuclei (arrows), negative nuclei
(arrowheads). The high background stain resulting
from this kit makes image analysis difficult
if not impossible.
ER 1-D5 (DakoCytomation) expression in normal
rat mammary gland. Detection with DakoCytomation
Envision+ HRP kit. Positive nuclei (arrows),
negative nuclei (arrowheads). This kit
uses a dextran coated polymer for detection
and delivers a very crisp, clean immuno stain.
The absence of biotin and streptavidin in the
system reduces background to a minimum.
ER (1-D5) expression in papillary adenocarcinoma.
The first layer of epithelium, adjacent to the
stromal tissue is negative for ER expression.
A similar pattern of expression is also seen
ER (1-D5)expression in cribriform adenocarcinoma.
Innermost epithelial cells comprising secondary
lumina are mostly negative. Mitotic figures
are indicated by arrowheads.
PR (PR88 Biogenex) expression in cribriform